Rheumatoid Factor – Purpose, Symptoms, Treatment, & Results

Rheumatoid Factors are proteins produced by your immune system that can attack healthy tissue in your body. High levels of rheumatoid factor in the blood are often associated with autoimmune diseases.

Rheumatoid Factor - Purpose, Symptoms, Treatment, & Results
Rheumatoid Factor – Purpose, Symptoms, Treatment, & Results

What is Rheumatoid factor?

A rheumatoid factor (RF) blood test measures the amount of RF antibody present in the blood. Typically, antibodies are produced by the immune system to help kill and destroy invasive bacteria that can cause disease. But RF antibodies can bind to body tissue, resulting in damage.


Sometimes your body might produce small amounts of RF without any medical problems. It is rare, and doctors do not fully understand why this happens.

What is the normal range for Rheumatoid factor?

The body is producing higher-than-average amounts of antibodies. It indicates a positive RF test. The idea of the prescribed values is given below-

  • Most medical centers consider the normal range of rheumatoid factor to be 10 IU / mL or 20 IU / mL, says rheumatologist Stephen Schulze, assistant professor at Penn Medicine in Philadelphia.
  • If the range starts at 20 and the person is 22 years old, then it is significantly less positive and may not be diagnostic, he says. As it may, if the rheumatoid factor limit is 600, more analytical weight may occur.
  • The category for the rheumatoid factor is less than 14 IU / ml. Any outcome with values ​​of 14 IU/mL or above is viewed as strangely high, raised, or positive.

Treatments of rheumatoid factor:-

Treatment for high RF relies upon treating the secret reason. In people with RA, the goal of treatment is to slow the progression of the disorder and help prevent or reduce symptoms.


There is no precise treatment of RA. However, effective, early treatment will prevent or slow the progression of the disease and prevent permanent joint damage.

What can cause high rheumatoid factor?

Many autoimmune diseases and infections can cause a high level of rheumatoid factor. Sometimes an elevated level of RF is present in healthy people.


Below are the methods to find the ratio of rheumatoid factor in the bloodstream

  • Agglutination test

A test method mixes blood with small rubber beads covered with human antibodies. If RF is present, latex beads collide.


This method was prior used as a screening test for arthritis. Another agglutination test involves testing blood with red blood cells of sheep with rabbit antibodies. If RF is present, the red blood cells collide.


This method is used mostly to confirm the presence of RF.


  • Nephelometry test


This test mixes the blood with antibodies that cause blood clots to form when RF is present. A laser light flashes on the mixing tube and the amount of light blocked by the blood sample is measured.


As the RF level increases, more clumping occurs, causing the cloud to sample and less light to pass through the tube.

How accurate is rheumatoid factor test?

Once you leave a sample of your blood in the laboratory, it can be tested for these factors:

  • Rheumatoid factor – RF antibodies accumulate in the synovium, or tissue lining, of your joints. They are present in the blood of many people with RA.
  • Erythrocyte sedimentation rate (ESR) – A high value of this type may indicate inflammation in your joints.
  • C-reactive protein (CRP) – The presence of this protein can also be a sign of inflammation in your joints.
  • Complete blood count – This includes hemoglobin and hematocrit tests, which can reveal anemia. It may also be associated with RA.

The RF test is not efficient enough to determine the RA. While many people with RA demonstrate this factor, some people do not. Also, some people who do not have status tests positive for RF due to other diseases or disorders, such as:

Here are some extra pointers we should know:-

Lower motor neuron-

Motor neurons are either most important in the retarded segment, front nerve roots, or cranial nerve core of the brainstem and cranial nerves with engine work.



Every single intentional development depends on the spinal cord’s lower engine neurons, which stress the fibers of skeletal muscles and the relationship between upper engine neurons and muscles.


The cranial nerves lower motor neurons control the movements of the eyes, face, and tongue, and contribute to chewing, swallowing, and vocalization.


Damage to the lower motor neurons may cause flaccid paralysis, absent deep tendon reflexes, and muscle atrophy.

Rheumatoid arthritis (RA)-

  • It is an immune system sickness that can cause joint torment and harm all through your body. The loss of RA usually occurs on both sides of the body.
  • It is one-way doctors distinguish RA from other forms of arthritis, such as osteoarthritis (OA). When one joint in a part of the hand or leg is in pain, the opposite side shows the response to it.
  • Treatment is best when diagnosed early with RA, so you need to learn the signs. Get to know everything about RA, from signs and symptoms to home remedies, diet, and other remedies.

Schmorl’s node-

Otherwise called an intervertebral plate herniation, the vertebral body alludes to the bulges of the ligament of the intervertebral circle through the endplate and neighboring vertebrae. Distensions may contact the vertebral medulla, causing aggravation.

How can I lower my rheumatoid factor?

According to clinical guidelines published in 2011, targeted physical therapy may benefit people with RF. It may include stretching, exercise, and alternative exercises between hot and cold.

  • Exercise –

In addition to performing targeted stretches, some dynamic, low-stress forms of exercise may benefit people with RF. Activities such as swimming or cycling can strengthen the muscles around the affected joints. It can help reduce the overall effect on joints and slow the progression of RF.

  • Stretching –

The muscles around the affected joints can provide some relief from RF symptoms. A 2015 study published in the Health Technology Assessment found that simple stretches and strengthening exercises can help reduce RF symptoms in the hands and wrists.

  • Heat and cold –

There is conflicting medical evidence about the benefits of applying heat or cold to relieve RA pain in joints. Some people get temporary relief by heating or cooling these wound areas. At home, a person may use heat or ice packs.

  • Lifestyle changes –

Some people with RA may benefit from reducing physical and emotional stress. Gentle methods of stress relief may include reflective meditation, tai chi, and yoga.


When to see a doctor-


Anyone who suspects to have RA or any other autoimmune condition should see a doctor.


Even if an RF test shows a negative result, the person should always check back with their doctor for a complete diagnosis. During diagnosis or treatment, the person showing new signs or symptoms should also visit their doctor to discuss the changes.

In the end,

The rheumatoid factors test measures the rheumatoid factor in your blood. Rheumatic variables are proteins distributed by your inappropriate structure that can attack the tissue in your body.


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