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Statin Drugs – Definition, Benefits, Side Fffects

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Statin Drugs are a group of drugs used to treat high cholesterol. They work by lowering the level of cholesterol in your blood, especially low-density lipoprotein or “bad” cholesterol.


Statin Drugs - Definition, Benefits, Side Fffects
Statin Drugs

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What are statin drugs and where are they used:-

Statin drugs are a class that brings down blood cholesterol levels. It also lowers cholesterol production by the liver. Statins restrain the protein in the liver to make cholesterol, called hydroxy.


Scientifically, statins are called HMG-COAs that reduce inhibitors.


The Heart Association recommends statin medications for some people. You and your doctor should consider statins for you if, 

  1. LDL cholesterol level is 190 mg / dL or more

  2. Already have heart disease

  3. Are the age of 40–75 years old and the risk of heart disease has increased over the next ten years

  4. Are diabetic, 40–75 years old, and has an LDL level between 70 and 189 mg / dL

Statin drug interactions need to be known:-

Some drug interactions of statins occur. The first type involves enzymes responsible for the elimination of statins from the liver.


Since they are responsible for destroying all statins from the body, including pravastatin and lovastatin. Drugs or agents that block these enzymes include:

  1. Protease inhibitor

  2. Erythromycin

  3. Itraconazole,

  4. clarithromycin,

  5. Telithromycin

  6. Cyclosporine

  7. Boceprevir

  8. Telaprevir

Side effects of statin drugs –  Waiting for the Benefit and Risk:-

Statins cause severe liver damage. More often, statins cause abnormalities in liver tests.


Abnormal tests usually become normal even if a statin is continued, but if the abnormal test value is more than three times the upper limit of normal, the statin is usually withheld.


The liver test should be measured before the onset of statins and if there is any concern about liver damage after that. Statins are effective in lowering cholesterol and protecting against heart attacks and strokes, although they can cause side effects for some people.

The most common side effects are – 


  1. Muscle pain and damage – One of the most well-known grumblings of individuals taking statins is muscle torment. You may feel this pain as a soreness, fatigue, or weakness in your muscles. 

  2. Liver damage – Sometimes, the use of statins can increase the levels of enzymes that indicate liver inflammation. If the increase is only mild, you can continue taking the medicine

  3. Increased blood sugar or type 2 diabetes – Your blood sugar level may increase while taking statins, which can lead to the development of type 2 diabetes. 

Statin drugs and diabetes –

Researchers said that statins increase the risk of type 2 diabetes in several ways. One is that drugs can increase a person’s insulin resistance, and another is that cholesterol-lowering drugs inhibit the pancreas’ ability to secrete insulin.


There is also evidence that statin may help with brain function. Do not stop taking your statin medication before talking to your doctor.

Alternatives to statin drugs:-

There are other ways that you can help lower your cholesterol, including lifestyle changes.

  1. Dietary changes – Some foods help reduce the risk of cholesterol and vessel disease, the soluble fiber in oatmeal, prunes, apples, pears, kidney beans, and barley.

  2. Quitting Smoking – If you smoke, stopping it can help improve your cholesterol levels.

  3. Exercising – Losing excess weight from 5 to 10 pounds, and regularly engaging in physical activity can improve your cholesterol numbers.

Few more options-

If you experience severe side effects or are not a statin candidate, your doctor may prescribe another type of medicine to treat your cholesterol levels.

  1. Cholesterol absorption inhibitor

  2. Bile acid sequential

  3. Combination cholesterol absorption inhibitors and statins

Is supplementation safe to take with statin drugs?

Yes, Supplements to take with statin drugs. For most people, Statin drugs are safe.

As with all medications, some who experience mild side effects, and others that have more severe side effects, including liver toxicity and muscle damage.


But statin drugs have been extensively studied, and data tells us that for most people, taking supplements with statin drugs is safe. 


Supplements from foods – which can also lower your cholesterol.

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Talk to your doctor about any supplement you are considering, especially if you are pregnant.

  1. Niacin – Niacin is a B vitamin. Doctors sometimes recommend it for patients with high cholesterol or heart concerns. It benefits you by increasing the level of good cholesterol and reducing triglycerides.

  2. Soluble fiber – There are two types of fiber: soluble, which dissolves in a gel in a liquid, and is insoluble. Soluble fiber reduces the absorption of cholesterol in your bloodstream.

  3. Psyllium supplements – Psyllium is a fiber made from the husk of the seed of the Plantago Ovata plant. You can take it in a pill or mix it in a drink or food. Taking Psyllium regularly has been assigned a source for significantly lowering cholesterol levels.

  4. Soy Protein – Soybeans and foods made with them can reduce LDL cholesterol slightly. Tofu, soy milk, and boiled soybeans are a good source of lean protein. 

  5. Flaxseed – Both its seeds and the oil extracted from them are good sources of omega-3 fatty acids, which have many health benefits, including increasing your HDL cholesterol levels.

How do Apple Cider Vinegar and Statin Drugs work:-

Apple Cider Vinegar-

It is a juice that is fermented with crushed apple and contains vitamins B1, B2 and B6, biotin, folic acid, niacin, pantothenic acid, and vitamin C.


Apple cider vinegar may also contain significant amounts of acetic acid and citric acid, besides is used to make medicine.

Statin drugs –

They are a class of drugs prescribed by doctors to help reduce blood cholesterol levels. By lowering the levels, they help prevent heart attacks and strokes.


Studies also suggest that statins can reduce the likelihood of recurrent stroke or heart attack by around 40%.

They work like this-

  1. Apple contains B vitamins and Vitamin C, acetic acid, and nutrients. Statin drugs are your body’s need for some cholesterol to work well.

  2. Apple cider vinegar can help reduce blood sugar levels in diabetic people, while statins work to control cholesterol levels. The body gets cholesterol by eating certain foods and making it in its liver. 

  3. Apple cider vinegar may prevent the breakdown of certain foods. Statins work by making it easier for your body to absorb cholesterol that formed in your arteries. Statins do this by stopping the production of an enzyme called HMG-COA reductase in your body.

Are Statins generics Advisable:-

  1. If you are taking cholesterol controlling drugs, then you know that the monthly cost can boom, especially if the one you are using is not available in the generic form. The total cost may be more than usual. Continue them only if prescribed.

  2. High cholesterol is not a symptom in itself, but you are not taking medication to stop the rise of cholesterol.

  3. Increasing your cholesterol levels again can increase your heart disease and even risk. Heart attack, compared to the cost of living on your cholesterol controlling drug, is more of a concern.

The good news is that many cholesterol-lowering drugs in inexpensive generics or statin brands. Available, these common cholesterol medications include:

  1. Simvastatin

  2. Lovastatin

  3. Atorvastatin

  4. Rosuvastatin

  5. Fluvastatin

  6. Pravastatin

  7. Gemfibrozil

  8. Fenofibrate

  9. Cholestyramine

Points About Non statin drugs-

Non-statin drugs for cholesterol-lowering are currently under FDA review.


The FDA has approved two new non-statin drugs that clinical trials indicate may help reduce high cholesterol.


Nexletol and Nexlizet have moderate or minimal side effects with statins. The two new drugs have some side effects different from those associated with statins.

The pharmaceutical industry has been relatively slow to deliver new equipment to medical professionals and consumers to fight high cholesterol, which can lead to heart disease and other health conditions.

Considering the pros and cons of statin drugs – Safe or not


Pros

  1. It reduces the effect of suppressed arteries.

  2. It helps fight inflammation, reducing artery damage.

  3. Statin drugs help prevent cholesterol from forming in the liver.

  4. They can also help control triglycerides and increase HDL levels.

Cons

  1. Its intake might make feel dizziness

  2. There is a risk of liver damage and kidney failure with grapes.

Combining the two suppresses the enzyme that helps the body make medicine. It balances how much it goes into the bloodstream. The compounds interfere with it and high amounts of the drug in the blood.

Wrapping up,


We want to tell you that statin drugs are a class of drugs prescribed for low blood cholesterol.


Statins are also prescribed for the prevention and treatment of atherosclerosis. For more information, and health-related articles stay connected with the team OnlyHealthCares.


Stay Healthy, Stay Safe! 

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